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KMID : 0882420150880060663
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Korean Journal of Medicine
2015 Volume.88 No. 6 p.663 ~ p.671
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Pyogenic Liver Abscess: Changes in Clinical Features over the Last 10 Years
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Park Joo-Ho
Lee Tae-Hee
Kang Min-Gyu
Lee Mi-Young
Lee Myung-Jun
Pyo Jin-Sil
Park Jung-Ho
Koo Hoon-Sup
Song Kyung-Ho
Kim Yong-Seok
Kim Sun-Moon
Huh Kyu-Chan
Choi Young-Woo
Kang Young Woo
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Abstract
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Background/Aims: A pyogenic liver abscess is an acute bacterial infection that can potentially lead to life-threatening sepsis. This study examined the clinical features and changing trends of pyogenic liver abscess over the last 10 years.
Methods: We investigated patient characteristics, laboratory findings, blood and abscess culture results, location and characteristics of the abscess, and treatment modality in the medical records of 146 patients. We divided them into three groups by period: period 1, 23 patients in 2002-2003; period 2, 46 patients in 2007-2008; and period 3, 77 patients in 2012-2013.
Results: The mean patient age was 64.3 ± 15.1 years and 87 of the 146 patients were male (59.6%). Period 2 had a higher prevalence of chronic alcoholics (30.4% vs. 10.4%) and lower prevalence of fever and chills (73.9% vs. 92.2%) compared with period 3. Klebsiella pneumoniae was the most commonly cultured bacteria and the microbiological findings did not differ among the three periods. Pyogenic liver abscesses were more common in the right liver. The lengths of hospital stay and treatment modalities were similar in all three periods.
Conclusions: Although there were slight differences in symptoms among the periods, there were no changes in the liver abscess characteristics, i.e., location, size, and culture results. As there were no changes, the treatment strategy also did not change. We should continue to investigate the clinical features of liver abscess.
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KEYWORD
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Liver abscess, Klebsiella pneumoniae, Drainage
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